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This chart is provided for information purposes only. Double check all your math, individual vial concentrations, etc. Different hospitals stock different brands and different concentrations!!
| Drug | Stock solution or Reconstitution instructions | Administration |
| Aminocaproic acid (EACA) 250mg/mL | Not refrigerated | Dilute to 20mg/mL with saline or D5W Give IV over 1 hour To dilute, draw up desired mg EACA then multiply volume x12.5, dilute to this volume with 0.9% NaCl Ex: 800mg EACA = 3.2mL 3.2 x 12.5 = 40mL total volume |
| Ampicillin sulbactam 30mg/mL (Safe for SQ or IM at 375mg/mL) | 1.5g vial: Use 50mL bag of 0.9% NaCl Remove 8mL and add to powder in vial Mix until dissolved Use new needle to remove contents of vial and inject back into the 50mL bag of 0.9% NaCl Mix well 3g vial: Use 100mL bag of 0.9% NaCl Remove 16mL and add to powder in vial Mix until dissolved Use new needle to remove contents of vial and inject back into the 100mL bag of 0.9% NaCl Mix well Good 72h refrigerated or 8 hours room temp | No further dilution necessary Give IV over 30 minutes |
| Cefazolin 100mg/mL (IM or SQ also safe) | Add 9.4mL sterile water to powder in vial Mix until dissolved Good 10 days refrigerated or 24h room temp | No further dilution necessary Give IV slow over 3-5 minutes |
| Cefovecin 80mg/mL (SQ only) | Add 10mL sterile water to powder in vial Mix until dissolved Good 56 days refrigerated; might turn a rust-brown color, this is okay | No further dilution necessary Give SQ |
| Cefoxitin 95mg/mL | 1g vial Add 10mL sterile water to vial Mix until dissolved Good 7 days refrigerated or 24h room temp | No further dilution necessary Give IV over 3-5 minutes |
| Ceftazidime 100mg/mL | 1g vial Add 10mL sterile water to vial Mix until dissolved Good 7 days refrigerated or 24h room temp | No further dilution necessary Give IV over 3-5 minutes |
| Clindamycin 150mg/mL (IM no dilution needed) | Not refrigerated | Dilute to 15mg/mL Give IV at max rate 1mL/min (60mL/h) To dilute, draw up desired mg clindamycin then multiply volume x10, dilute to this volume with 0.9% NaCl Ex: 75mg clindamycin = 0.5mL 0.5 x 10 = 5mL total volume |
| Doxycycline 10mg/mL | Add 10mL sterile water to powder in vial Mix until fully dissolved Good 72h refrigerated or 6 hours room temp Protect from light with amber vial or bag Good for 12h once diluted for IV administration | Dilute to 1mg/mL Give IV over 2 hours; protect from light during infusion To dilute, draw up desired mg of doxycycline and multiply volume by 10. Dilute to this volume with saline. Ex: 30mg doxycycline = draw up 3cc of doxycycline 10mg/mL and dilute to 30mL with saline |
| Enrofloxacin 22.7mg/mL (IM no dilution needed; do not give SQ) | Not refrigerated Not compatible with LRS, Plasmalyte A, Normosol R | Dilute to 1mL/kg (this is approx. 1:5 dilution when dosed at 5mg/kg) with 0.9% NaCl STOP IV fluids, flush line before and after infusion Or give in separate IV catheter Give IV over 30 minutes Can also give 22.7mg/mL IM |
| Levetiracetam 100mg/mL | Not refrigerated | Dilute to 10mg/mL Give IV over 15 minutes To dilute, draw up desired mg levetiracetam then multiply volume x10, dilute to this volume with 0.9% NaCl Ex: 200mg levetiracetam = 2mL 2 x 10 = 20mL total volume |
| Metronidazole 5mg/mL IV only | Not refrigerated Protect from light | No further dilution necessary Give IV over 1 hour |
| N-Acetylcysteine (NAC) 200mg/mL | Not refrigerated | Dilute to 33mg/mL with D5W Give IV over 20 minutes To dilute, draw up desired mg NAC then multiply volume x6, dilute to this volume with 0.9% D5W Ex: 500mg NAC = 2.5mL 2.5 x 6 = 15mL total volume |
| Pantoprazole 0.8mg/mL IV only, do not give SQ or IM | Use 50mL bag 0.9% NaCl Draw out 10mL from bag and add to vial Mix until dissolved Remove entire contents of vial and add to same 50mL bag of 0.9% NaCl Good 11 days refrigerated or 24h room temp | No further dilution necessary Give IV over 15 minutes |
| Phenobarbital 130mg/mL | Not refrigerated | No dilution needed Give IV slow over 3-5 minutes |
| Voriconazole 2mg/mL | Use 100mL bag 0.9% NaCl Remove 19mL from bag and add to powder in vial Mix until dissolved Add entire contents of vial back to 100mL bag of 0.9% NaCl Mix well Good 15 days refrigerated or 3 days room temp | No further dilution necessary Give IV over 2 hours |
| Last update: 23Sep20 |
